stem cell treatment - An Overview
With the concept a far more rapid cell cycle is a vital element of pluripotency, reprogramming effectiveness is often enhanced. Procedures for strengthening pluripotency by manipulation of cell cycle regulators consist of: overexpression of Cyclin D/Cdk4, phosphorylation of Sox2 at S39 and S253, overexpression of Cyclin A and Cyclin E, knockdown of